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GPHN Antibody

Product Specifications

Background

GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency.

NCBI Gene ID

10243

Swiss Prot

Q9NQX3

Accession Number

Q9NQX3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GPHN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human GPHN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=64-114

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

GPHN

NCBI Official Name

Gephyrin

NCBI Organism

Homo sapiens

Background Reference 01

Tabakoff, B., et al. BMC Biol. 7, 70 (2009)

Background Reference 02

Fritschy, J.M., et al. Trends Neurosci. 31 (5) :257-264 (2008)

Background Reference 03

Inada, T., et al. Pharmacogenet. Genomics 18 (4) :317-323 (2008)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

Gephyrin, Molybdopterin adenylyltransferase, MPT adenylyltransferase, Domain G, Molybdopterin molybdenumtransferase, MPT Mo-transferase, Domain E, GPHN, GPH, KIAA1385

Tested Applications

WB, IHC-P, Flow

Protein ID

13431554

Physical Properties

Liquid

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