ST8SIA4 Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus.

NCBI Gene ID

7903

Swiss Prot

Q92187

Accession Number

Q92187

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ST8SIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human ST8SIA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

ST8SIA4

NCBI Official Name

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Johnson, M.P., et al. Hum. Genet. 126 (5) :655-666 (2009)

Background Reference 02

Foley, D.A., et al. J. Biol. Chem. 284 (23) :15505-15516 (2009)

Background Reference 03

Otowa, T., et al. J. Hum. Genet. 54 (2) :122-126 (2009)

Background Reference 04

Sonuga-Barke, E.J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :

Other Product Names

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase, 2499-, Alpha-2,8-sialyltransferase 8D, Polysialyltransferase-1, Sialyltransferase 8D, SIAT8-D, Sialyltransferase St8Sia IV, ST8SiaIV, ST8SIA4, PST, PST1, SIAT8D