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RXRB Antibody

Product Specifications

Background

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA) . This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

NCBI Gene ID

6257

Swiss Prot

P28702

Accession Number

P28702

Host

Rabbit

Reactivity

Human

Immunogen

This RXRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-284 amino acids from the Central region of human RXRB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RXRB

NCBI Official Name

Retinoic acid receptor RXR-beta

NCBI Organism

Homo sapiens

Background Reference 01

Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

Background Reference 02

Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

Background Reference 03

Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009)

Background Reference 04

Kalsch, A.I., et al. Autoimmunity 42 (5) :467-474 (2009)

Other Product Names

Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta, RXRB, NR2B2

Tested Applications

WB

Protein ID

1350911

Physical Properties

Liquid

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