NDUFS2 Antibody

Product Specifications

Background

NDUFS2 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria.

NCBI Gene ID

4720

Swiss Prot

O75306

Accession Number

O75306

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NDUFS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human NDUFS2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

NDUFS2

NCBI Official Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Saada, A., et al. Am. J. Hum. Genet. 84 (6) :718-727 (2009) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008) Starr, J.M., et al. Mech. Ageing Dev. 129 (12) :745-751 (2008) Ban, M., et al. PLoS ONE (8), E2891 (2008) Triepels, R.H., et al. J. Biol. Chem. 276 (12) :8892-8897 (2001)