TMIE Antibody
Product Specifications
Background
This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.
NCBI Gene ID
259236
Swiss Prot
Q8NEW7
Accession Number
Q8NEW7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TMIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the Central region of human TMIE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TMIE
NCBI Official Name
Transmembrane inner ear expressed protein
NCBI Organism
Homo sapiens
Background Reference 01
Yang, J.J., et al. Int. J. Pediatr. Otorhinolaryngol. (2010) In press
Background Reference 02
Sirmaci, A., et al. Clin. Genet. 75 (6) :562-567 (2009)
Background Reference 03
Santos, R.L., et al. J. Mol. Med. 84 (3) :226-231 (2006)
Background Reference 04
Cho, K.I., et al. Comp. Med. 53 (6) :642-648 (2003)
Other Product Names
Transmembrane inner ear expressed protein, TMIE
Tested Applications
WB
Protein ID
212276469
Physical Properties
Liquid
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