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ANKH Antibody

Product Specifications

Background

ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.

NCBI Gene ID

56172

Swiss Prot

Q9HCJ1

Accession Number

Q9HCJ1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ANKH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-492 amino acids from the C-terminal region of human ANKH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

ANKH

NCBI Official Name

Progressive ankylosis protein homolog

NCBI Organism

Homo sapiens

Background Reference 01

Wang, J., et al. J. Rheumatol. 36 (6) :1265-1272 (2009)

Background Reference 02

Ho, A.M., et al. Science 289 (5477) :265-270 (2000)

Background Reference 03

Rojas, K., et al. Genomics 62 (2) :177-183 (1999)

Other Product Names

Progressive ankylosis protein homolog, ANK, ANKH, KIAA1581

Tested Applications

WB, IHC-P, Flow

Protein ID

17366849

Physical Properties

Liquid

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