DCLRE1C Antibody
Product Specifications
Background
DCLRE1C is a nuclear protein that is involved in V (D) J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.
NCBI Gene ID
64421
Swiss Prot
Q96SD1
Accession Number
Q96SD1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DCLRE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human DCLRE1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
78 kDa
Fragment
Rabbit Ig
Symbol
DCLRE1C
NCBI Official Name
Protein artemis
NCBI Organism
Homo sapiens
Background Reference 01
Beucher, A., et al. EMBO J. 28 (21) :3413-3427 (2009)
Background Reference 02
Rivera-Munoz, P., et al. Blood 114 (17) :3601-3609 (2009)
Background Reference 03
Wang, H., et al. J. Biol. Chem. 284 (27) :18236-18243 (2009)
Other Product Names
Protein artemis, 31--, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein, DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C
Tested Applications
WB, IHC-P
Protein ID
71153325
Physical Properties
Liquid
Frequently Asked Questions
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