DCLRE1C Antibody

Product Specifications

Background

DCLRE1C is a nuclear protein that is involved in V (D) J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.

NCBI Gene ID

64421

Swiss Prot

Q96SD1

Accession Number

Q96SD1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DCLRE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human DCLRE1C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Symbol

DCLRE1C

NCBI Official Name

Protein artemis

NCBI Organism

Homo sapiens

Background Reference 01

Beucher, A., et al. EMBO J. 28 (21) :3413-3427 (2009)

Background Reference 02

Rivera-Munoz, P., et al. Blood 114 (17) :3601-3609 (2009)

Background Reference 03

Wang, H., et al. J. Biol. Chem. 284 (27) :18236-18243 (2009)

Other Product Names

Protein artemis, 31--, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein, DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C