PDE6C Antibody

Product Specifications

Background

PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.

NCBI Gene ID

5146

Swiss Prot

P51160

Accession Number

P51160

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PDE6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human PDE6C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

99 kDa

Fragment

Rabbit Ig

Applications Notes

For IHC-P starting dilution is: 1:50~100

Symbol

PDE6C

NCBI Official Name

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

NCBI Organism

Homo sapiens

Background Reference 01

Muradov, H., et al. J. Biol. Chem. 284 (47) :32662-32669 (2009) Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (46) :19581-19586 (2009) Thiadens, A.A., et al. Am. J. Hum. Genet. 85 (2) :240-247 (2009)