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ADH7 Antibody

Product Specifications

Background

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members.

NCBI Gene ID

131

Swiss Prot

P40394

Accession Number

P40394

Host

Rabbit

Reactivity

Human

Immunogen

This ADH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of human ADH7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

ADH7

NCBI Official Name

Alcohol dehydrogenase class 4 mu/sigma chain

NCBI Organism

Homo sapiens

Background Reference 01

Kedishvili, N.Y., et al. J. Biol. Chem. 270 (8) :3625-3630 (1995)

Background Reference 02

Cheung, B., et al. Alcohol. Clin. Exp. Res. 19 (1) :185-186 (1995)

Background Reference 03

Farres, J., et al. Eur. J. Biochem. 224 (2) :549-557 (1994)

Background Reference 04

Pares, X., et al. FEBS Lett. 303 (1) :69-72 (1992)

Other Product Names

Alcohol dehydrogenase class 4 mu/sigma chain, Alcohol dehydrogenase class IV mu/sigma chain, Gastric alcohol dehydrogenase, Retinol dehydrogenase, ADH7

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

292495000

Physical Properties

Liquid

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