INSC Antibody

Product Specifications

Background

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]) .

NCBI Gene ID

387755

Swiss Prot

Q1MX18

Accession Number

Q1MX18

Host

Rabbit

Reactivity

Human

Immunogen

This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the Central region of human INSC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Symbol

INSC

NCBI Official Name

Protein inscuteable homolog

NCBI Organism

Homo sapiens

Background Reference 01

Vural, A., et al. Mol. Cell. Biol. 30 (6) :1528-1540 (2010)

Background Reference 02

Rivadeneira, F., et al. Nat. Genet. 41 (11) :1199-1206 (2009)

Background Reference 03

Izaki, T., et al. Biochem. Biophys. Res. Commun. 341 (4) :1001-1006 (2006)

Background Reference 04

Katoh, M., et al. Int. J. Mol. Med. 11 (1) :111-116 (2003)

Other Product Names

Protein inscuteable homolog, INSC

Tested Applications

WB, IHC-P

Protein ID

116248172

Physical Properties

Liquid

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