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HFE2 Antibody

Product Specifications

Background

HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin.

NCBI Gene ID

148738

Swiss Prot

Q6ZVN8

Accession Number

Q6ZVN8

Host

Rabbit

Reactivity

Human

Immunogen

This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human HFE2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

HFE2

NCBI Official Name

Hemojuvelin

NCBI Organism

Homo sapiens

Background Reference 01

Zhu, X., et al. Genet. Epidemiol. 34 (2) :171-187 (2010)

Background Reference 02

Barton, J.C., et al. Am. J. Hematol. 84 (11) :710-714 (2009)

Background Reference 03

Zhang, A.S., et al. J. Biol. Chem. 284 (34) :22580-22589 (2009)

Other Product Names

Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC

Tested Applications

WB, IHC-P

Protein ID

51316254

Physical Properties

Liquid

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