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KRT1 Antibody

Product Specifications

Background

KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

NCBI Gene ID

3848

Swiss Prot

P04264

Accession Number

P04264

Host

Rabbit

Reactivity

Human

Immunogen

This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of human KRT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Symbol

KRT1

NCBI Official Name

Keratin, type II cytoskeletal 1

NCBI Organism

Homo sapiens

Background Reference 01

Labudova, M., et al. J. Virol. 83 (16) :7842-7849 (2009)

Background Reference 02

Barcelos, A.C., et al. J. Cutan. Pathol. 36 (6) :647-654 (2009)

Background Reference 03

Grimberg, G., et al. Br. J. Dermatol. 160 (2) :446-449 (2009)

Other Product Names

Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA

Tested Applications

WB, IHC-P, Flow

Protein ID

238054406

Physical Properties

Liquid

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