ERF3B Antibody

Product Specifications

Background

ERF3B encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.

NCBI Gene ID

23708

Swiss Prot

Q8IYD1

Accession Number

Q8IYD1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ERF3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the Central region of human ERF3B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GSPT2

NCBI Official Name

Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

NCBI Organism

Homo sapiens

Background Reference 01

Cheng, Z., et al. Genes Dev. 23 (9) :1106-1118 (2009)

Background Reference 02

Zhouravleva, G., et al. IUBMB Life 58 (4) :199-202 (2006)

Background Reference 03

Chauvin, C., et al. Mol. Cell. Biol. 25 (14) :5801-5811 (2005)

Background Reference 04

Hoshino, S., et al. J. Biol. Chem. 274 (24) :16677-16680 (1999)

Other Product Names

Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, Eukaryotic peptide chain release factor subunit 3b, eRF3b, G1 to S phase transition protein 2 homolog, GSPT2, ERF3B