C9orf95 Antibody

Product Specifications

Background

Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]) .[supplied by OMIM].

NCBI Gene ID

54981

Swiss Prot

Q9NWW6

Accession Number

Q9NWW6

Host

Rabbit

Reactivity

Human

Immunogen

This C9orf95 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-50 amino acids from the N-terminal region of human C9orf95.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NMRK1

NCBI Official Name

Nicotinamide riboside kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Khan, J.A., et al. Structure 15 (8) :1005-1013 (2007)

Background Reference 02

Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

Background Reference 03

Bieganowski, P., et al. Cell 117 (4) :495-502 (2004)

Other Product Names

Nicotinamide riboside kinase 1, NRK 1, NmR-K 1, Nicotinic acid riboside kinase 1, Ribosylnicotinamide kinase 1, RNK 1, Ribosylnicotinic acid kinase 1, NMRK1, C9orf95, NRK1