B3GNT5 Antibody
Product Specifications
Background
B3GNT5 is a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.
NCBI Gene ID
84002
Swiss Prot
Q9BYG0
Accession Number
Q9BYG0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This B3GNT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human B3GNT5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=64-048
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
B3GNT5
NCBI Official Name
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Marcos, N.T., et al. J. Clin. Invest. 118 (6) :2325-2336 (2008)
Background Reference 02
Togayachi, A., et al. J. Biol. Chem. 276 (25) :22032-22040 (2001)
Other Product Names
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide synthase, Lc (3) Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5, B3GNT5
Tested Applications
WB
Protein ID
74733473
Physical Properties
Liquid
Curated Selection
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