B3GNT5 Antibody

Product Specifications

Background

B3GNT5 is a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.

NCBI Gene ID

84002

Swiss Prot

Q9BYG0

Accession Number

Q9BYG0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This B3GNT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human B3GNT5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

B3GNT5

NCBI Official Name

Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Marcos, N.T., et al. J. Clin. Invest. 118 (6) :2325-2336 (2008)

Background Reference 02

Togayachi, A., et al. J. Biol. Chem. 276 (25) :22032-22040 (2001)

Other Product Names

Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide synthase, Lc (3) Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5, B3GNT5