NPW Antibody
Product Specifications
Background
NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq].
NCBI Gene ID
283869
Swiss Prot
Q8N729
Accession Number
Q8N729
Host
Rabbit
Reactivity
Human
Immunogen
This NPW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the C-terminal region of human NPW.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=64-046
Calculated Molecular Weight
18 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NPW
NCBI Official Name
Neuropeptide W
NCBI Organism
Homo sapiens
Background Reference 01
Luttrell, L.M. Mol. Biotechnol. 39 (3) :239-264 (2008)
Background Reference 02
Singh, G., et al. Br. J. Pharmacol. 148 (8) :1033-1041 (2006)
Other Product Names
Neuropeptide W, Preproprotein L8, hPPL8, Neuropeptide W-23, NPW23, hL8, Neuropeptide W-30, NPW30, hL8C, NPW, PPL8, PPNPW
Tested Applications
WB
Physical Properties
Liquid
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