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NPW Antibody

Product Specifications

Background

NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq].

NCBI Gene ID

283869

Swiss Prot

Q8N729

Accession Number

Q8N729

Host

Rabbit

Reactivity

Human

Immunogen

This NPW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the C-terminal region of human NPW.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NPW

NCBI Official Name

Neuropeptide W

NCBI Organism

Homo sapiens

Background Reference 01

Luttrell, L.M. Mol. Biotechnol. 39 (3) :239-264 (2008)

Background Reference 02

Singh, G., et al. Br. J. Pharmacol. 148 (8) :1033-1041 (2006)

Other Product Names

Neuropeptide W, Preproprotein L8, hPPL8, Neuropeptide W-23, NPW23, hL8, Neuropeptide W-30, NPW30, hL8C, NPW, PPL8, PPNPW

Tested Applications

WB

Physical Properties

Liquid

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