RAB3GAP2 Antibody

Product Specifications

Background

RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment.

NCBI Gene ID

25782

Swiss Prot

Q9H2M9

Accession Number

Q9H2M9

Host

Rabbit

Reactivity

Human

Immunogen

This RAB3GAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 943-972 amino acids from the C-terminal region of human RAB3GAP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

156 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RAB3GAP2

NCBI Official Name

Rab3 GTPase-activating protein non-catalytic subunit

NCBI Organism

Homo sapiens

Background Reference 01

Niwa, S., et al. Nat. Cell Biol. 10 (11) :1269-1279 (2008)

Background Reference 02

Ng, E.L., et al. Brain Res Rev 58 (1) :236-246 (2008)

Other Product Names

Rab3 GTPase-activating protein non-catalytic subunit, RGAP-iso, Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunit, RAB3GAP2, KIAA0839