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ABCD2 Antibody

Product Specifications

Background

ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.

NCBI Gene ID

225

Swiss Prot

Q9UBJ2

Accession Number

Q9UBJ2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ABCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the Central region of human ABCD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ABCD2

NCBI Official Name

ATP-binding cassette sub-family D member 2

NCBI Organism

Homo sapiens

Background Reference 01

Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)

Background Reference 02

Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377 (1) :176-180 (2008)

Background Reference 03

Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

Other Product Names

ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR, ABCD2, ALD1, ALDL1, ALDR, ALDRP

Tested Applications

WB

Protein ID

12643305

Physical Properties

Liquid

Frequently Asked Questions

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