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CHAT Antibody

Product Specifications

Background

CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease.

NCBI Gene ID

1103

Swiss Prot

P28329

Accession Number

P28329

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CHAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-128 amino acids from the N-terminal region of human CHAT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Symbol

CHAT

NCBI Official Name

Choline O-acetyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Shaffer, J.R., et al. Nutr Metab Cardiovasc Dis (2010) In press

Background Reference 02

Beck, M., et al. Cell Tissue Res. 338 (1) :37-51 (2009)

Background Reference 03

Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

Other Product Names

Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase, CHAT

Tested Applications

WB, IF

Protein ID

281185509

Physical Properties

Liquid

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