MORG1 Antibody

Product Specifications

Background

MORG1 is a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome.

NCBI Gene ID

84292

Swiss Prot

Q9BRX9

Accession Number

Q9BRX9

Host

Rabbit

Reactivity

Human

Immunogen

This MORG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human MORG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

WDR83

NCBI Official Name

WD repeat domain-containing protein 83

NCBI Organism

Homo sapiens

Background Reference 01

Haase, D., et al. Neurosci. Lett. 455 (1) :46-50 (2009)

Background Reference 02

Hopfer, U., et al. J. Biol. Chem. 281 (13) :8645-8655 (2006)

Background Reference 03

Vomastek, T., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (18) :6981-6986 (2004)

Other Product Names

WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83, MORG1

Tested Applications

Protein ID

74761224

Physical Properties

Liquid

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