NOXA1 Antibody

Product Specifications

Background

NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS) . The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]) .[supplied by OMIM].

NCBI Gene ID

10811

Swiss Prot

Q86UR1

Accession Number

Q86UR1

Host

Rabbit

Reactivity

Human

Immunogen

This NOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the C-terminal region of human NOXA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NOXA1

NCBI Official Name

NADPH oxidase activator 1

NCBI Organism

Homo sapiens

Background Reference 01

Niu, X.L., et al. Circulation 121 (4) :549-559 (2010)

Background Reference 02

Pacquelet, S., et al. J. Biol. Chem. 283 (36) :24649-24658 (2008)

Background Reference 03

Honjo, T., et al. Endothelium 15 (3) :137-141 (2008)

Background Reference 04

Kim, J.S., et al. J. Biol. Chem. 282 (48) :34787-34800 (2007)

Other Product Names

NADPH oxidase activator 1, NOX activator 1, Antigen NY-CO-31, NCF2-like protein, P67phox-like factor, p51-nox, NOXA1, P51NOX

Tested Applications

Protein ID

74759404

Physical Properties

Liquid

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