SPRR1A Antibody
Product Specifications
Background
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
NCBI Gene ID
6698
Swiss Prot
P35321
Accession Number
P35321
Host
Rabbit
Reactivity
Human
Immunogen
This SPRR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the C-terminal region of human SPRR1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
10 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SPRR1A
NCBI Official Name
Cornifin-A
NCBI Organism
Homo sapiens
Background Reference 01
Jarzab, J., et al. Int. Arch. Allergy Immunol. 151 (1) :28-37 (2010)
Background Reference 02
Stemmler, S., et al. Int. J. Immunogenet. 36 (4) :217-222 (2009)
Background Reference 03
Kainu, K., et al. Exp. Dermatol. 18 (2) :109-115 (2009)
Background Reference 04
Bonilla, I.E., et al. J. Neurosci. 22 (4) :1303-1315 (2002)
Other Product Names
Cornifin-A, 19 kDa pancornulin, SPRK, Small proline-rich protein IA, SPR-IA, SPRR1A
Tested Applications
WB
Protein ID
215273890
Physical Properties
Liquid
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