GBE1 Antibody
Product Specifications
Background
GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease) .
NCBI Gene ID
2632
Swiss Prot
Q04446
Accession Number
Q04446
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the Central region of human GBE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-981
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
GBE1
NCBI Official Name
1,4-alpha-glucan-branching enzyme
NCBI Organism
Homo sapiens
Background Reference 01
Konstantinidou, A.E., et al. Placenta 29 (4) :378-381 (2008)
Background Reference 02
Massa, R., et al. Muscle Nerve 37 (4) :530-536 (2008)
Background Reference 03
Bruno, C., et al. Acta Myol 26 (1) :75-78 (2007)
Other Product Names
4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme, GBE1
Tested Applications
WB, IF
Protein ID
357529509
Physical Properties
Liquid
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