GEN1 Antibody
Product Specifications
Background
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded (By similarity) .
NCBI Gene ID
348654
Swiss Prot
Q17RS7
Accession Number
Q17RS7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human GEN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
103 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GEN1
NCBI Official Name
Flap endonuclease GEN homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Ip, S.C., et al. Nature 456 (7220) :357-361 (2008)
Background Reference 02
Ishikawa, G., et al. Nucleic Acids Res. 32 (21) :6251-6259 (2004)
Other Product Names
Flap endonuclease GEN homolog 1, 31--, GEN1
Tested Applications
WB
Protein ID
290457644
Physical Properties
Liquid
Curated Selection
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