BRS3 Antibody

Product Specifications

Background

Mammalian bombesin-like peptides (see MIM 137260) are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor (MIM 305670), neuromedin B receptor (MIM 162341), and bombesin-like receptor-3 (BRS3) (Ohki-Hamazaki et al., 1997) .

NCBI Gene ID

680

Swiss Prot

P32247

Accession Number

P32247

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BRS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human BRS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BRS3

NCBI Official Name

Bombesin receptor subtype-3

NCBI Organism

Homo sapiens

Background Reference 01

Wang, Y., et al. Cell Biol. Int. 31 (12) :1495-1500 (2007)

Background Reference 02

Tan, Y.R., et al. Biochem. J. 405 (1) :131-137 (2007)

Background Reference 03

Hou, X., et al. Lung Cancer 54 (2) :143-148 (2006)

Background Reference 04

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Other Product Names

Bombesin receptor subtype-3, BRS-3, BRS3

Tested Applications

Protein ID

416726

Physical Properties

Liquid

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