BRS3 Antibody
Product Specifications
Background
Mammalian bombesin-like peptides (see MIM 137260) are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor (MIM 305670), neuromedin B receptor (MIM 162341), and bombesin-like receptor-3 (BRS3) (Ohki-Hamazaki et al., 1997) .
NCBI Gene ID
680
Swiss Prot
P32247
Accession Number
P32247
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This BRS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human BRS3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BRS3
NCBI Official Name
Bombesin receptor subtype-3
NCBI Organism
Homo sapiens
Background Reference 01
Wang, Y., et al. Cell Biol. Int. 31 (12) :1495-1500 (2007)
Background Reference 02
Tan, Y.R., et al. Biochem. J. 405 (1) :131-137 (2007)
Background Reference 03
Hou, X., et al. Lung Cancer 54 (2) :143-148 (2006)
Background Reference 04
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Other Product Names
Bombesin receptor subtype-3, BRS-3, BRS3
Tested Applications
WB
Protein ID
416726
Physical Properties
Liquid
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