IL2RG Antibody

Product Specifications

Background

IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

NCBI Gene ID

3561

Swiss Prot

P31785

Accession Number

P31785

Host

Rabbit

Reactivity

Human

Immunogen

This IL2RG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-101 amino acids from the N-terminal region of human IL2RG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

IL2RG

NCBI Official Name

Cytokine receptor common subunit gamma

NCBI Organism

Homo sapiens

Background Reference 01

Ross, J.A., et al. J. Biol. Chem. 285 (6) :3582-3591 (2010)

Background Reference 02

Ameratunga, R., et al. N. Z. Med. J. 122 (1304) :46-53 (2009)

Background Reference 03

Clark, P.A., et al. Hum. Genet. 96 (4) :427-432 (1995)

Other Product Names

Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132, IL2RG