MAFA Antibody
Product Specifications
Background
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.
NCBI Gene ID
389692
Swiss Prot
Q8NHW3
Accession Number
Q8NHW3
Host
Rabbit
Reactivity
Human
Immunogen
This MAFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-311 amino acids from the C-terminal region of human MAFA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAFA
NCBI Official Name
Transcription factor MafA
NCBI Organism
Homo sapiens
Background Reference 01
Kondo, T., et al. Mol. Endocrinol. 23 (8) :1281-1290 (2009)
Background Reference 02
Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009)
Background Reference 03
Garin, I., et al. Diabet. Med. 26 (7) :746-748 (2009)
Background Reference 04
Vanderford, N.L., et al. Arch. Biochem. Biophys. 480 (2) :138-142 (2008)
Other Product Names
Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Tested Applications
WB
Protein ID
296435511
Physical Properties
Liquid
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