HNF4A Antibody

Product Specifications

Background

HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines.

NCBI Gene ID

3172

Swiss Prot

P41235

Accession Number

P41235

Host

Rabbit

Reactivity

Human

Immunogen

This HNF4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-139 amino acids from the N-terminal region of human HNF4A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

HNF4A

NCBI Official Name

Hepatocyte nuclear factor 4-alpha

NCBI Organism

Homo sapiens

Background Reference 01

Koh, W., et al. BMC Genomics 11 SUPPL 1, S6 (2010)

Background Reference 02

Wang, F., et al. Chin. Med. J. 122 (20) :2477-2482 (2009)

Background Reference 03

Taghavi, S.M., et al. Cardiovasc Diabetol 8, 63 (2009)

Background Reference 04

Guo, H., et al. Biochem. J. 394 (PT 2), 379-387 (2006)

Other Product Names

Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14