SERPINA1 Antibody

Product Specifications

Background

SERPINA1 is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease.

NCBI Gene ID

5265

Swiss Prot

P01009

Accession Number

P01009

Host

Rabbit

Reactivity

Human

Immunogen

This SERPINA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SERPINA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SERPINA1

NCBI Official Name

Alpha-1-antitrypsin

NCBI Organism

Homo sapiens

Background Reference 01

Kilty, S.J., et al. AmRhinol Allergy 24 (1), E4-E9 (2010)

Background Reference 02

Kok, K.F., et al. BMC Gastroenterol 10, 22 (2010)

Background Reference 03

Dahl, M. Clin Respir3 (2) :121-122 (2009)

Background Reference 04

Zhang, H., et al. Nat. Biotechnol. 21 (6) :660-666 (2003)

Other Product Names

Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI

Tested Applications

Protein ID

1703025

Physical Properties

Liquid

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