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AGR3 Antibody

Product Specifications

Background

AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.

NCBI Gene ID

155465

Swiss Prot

Q8TD06

Accession Number

Q8TD06

Host

Rabbit

Reactivity

Human

Immunogen

This AGR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the C-terminal region of human AGR3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Symbol

AGR3

NCBI Official Name

Anterior gradient protein 3 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Persson, S., et al. Mol. Phylogenet. Evol. 36 (3) :734-740 (2005)

Background Reference 02

Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)

Background Reference 03

Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

Background Reference 04

Fletcher, G.C., et al. Br. J. Cancer 88 (4) :579-585 (2003)

Other Product Names

Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11

Tested Applications

WB, IHC-P, Flow

Protein ID

66774045

Physical Properties

Liquid

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