CPLX1 Antibody

Product Specifications

Background

CPLX1 encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.

NCBI Gene ID

10815

Swiss Prot

O14810

Accession Number

O14810

Host

Rabbit

Reactivity

Mouse

Immunogen

This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the Central region of human CPLX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Symbol

CPLX1

NCBI Official Name

Complexin-1

NCBI Organism

Homo sapiens

Background Reference 01

Salimi, K., et al. Synapse 62 (4) :273-282 (2008)

Background Reference 02

Giraudo, C.G., et al. Science 313 (5787) :676-680 (2006)

Background Reference 03

Kishi, T., et al. Schizophr. Res. 82 (2-3), 185-189 (2006) :

Background Reference 04

Basso, M., et al. Proteomics 4 (12) :3943-3952 (2004)

Other Product Names

Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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