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PNPO Antibody

Product Specifications

Background

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.

NCBI Gene ID

55163

Swiss Prot

Q9NVS9

Accession Number

Q9NVS9

Host

Rabbit

Reactivity

Human

Immunogen

This PNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PNPO.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PNPO

NCBI Official Name

Pyridoxine-5'-phosphate oxidase

NCBI Organism

Homo sapiens

Background Reference 01

Musayev, F.N., et al. J. Biol. Chem. 284 (45) :30949-30956 (2009)

Background Reference 02

Khayat, M., et al. Mol. Genet. Metab. 94 (4) :431-434 (2008)

Background Reference 03

Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :

Background Reference 04

Mills, P.B., et al. Hum. Mol. Genet. 14 (8) :1077-1086 (2005)

Other Product Names

Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO

Tested Applications

WB

Protein ID

37082126

Physical Properties

Liquid

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