PLCB1 Antibody
Product Specifications
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
NCBI Gene ID
23236
Swiss Prot
Q9NQ66
Accession Number
Q9NQ66
Host
Rabbit
Reactivity
Human
Immunogen
This PLCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the C-terminal region of human PLCB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
139 kDa
Fragment
Rabbit Ig
Symbol
PLCB1
NCBI Official Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
NCBI Organism
Homo sapiens
Background Reference 01
Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)
Background Reference 02
Woodcock, E.A., et al. J. Mol. Cell. Cardiol. 47 (5) :676-683 (2009)
Background Reference 03
Zhang, Y., et al. J. Recept. Signal Transduct. Res. 29 (1) :52-62 (2009)
Other Product Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, PLC-I, Phospholipase C-beta-1, PLC-beta-1, PLCB1, KIAA0581
Tested Applications
WB, Flow
Protein ID
12643814
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
19371154 3x 1.0 µg DNA
EPM2A CRISPR All-in-one AAV vector set (with saCas9)(Mouse)
Sign In for Pricing
View Details 