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PLCB1 Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.

NCBI Gene ID

23236

Swiss Prot

Q9NQ66

Accession Number

Q9NQ66

Host

Rabbit

Reactivity

Human

Immunogen

This PLCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the C-terminal region of human PLCB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-915

Calculated Molecular Weight

139 kDa

Fragment

Rabbit Ig

Symbol

PLCB1

NCBI Official Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)

Background Reference 02

Woodcock, E.A., et al. J. Mol. Cell. Cardiol. 47 (5) :676-683 (2009)

Background Reference 03

Zhang, Y., et al. J. Recept. Signal Transduct. Res. 29 (1) :52-62 (2009)

Other Product Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, PLC-I, Phospholipase C-beta-1, PLC-beta-1, PLCB1, KIAA0581

Tested Applications

WB, Flow

Protein ID

12643814

Physical Properties

Liquid

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