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HSD17B12 Antibody

Product Specifications

Background

The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.

NCBI Gene ID

51144

Swiss Prot

Q53GQ0

Accession Number

Q53GQ0

Host

Rabbit

Reactivity

Human

Immunogen

This HSD17B12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the Central region of human HSD17B12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

HSD17B12

NCBI Official Name

Estradiol 17-beta-dehydrogenase 12

NCBI Organism

Homo sapiens

Background Reference 01

Plourde, M. J. Steroid Biochem. Mol. Biol. 116 (3-5), 134-153 (2009)

Background Reference 02

Nagasaki, S. Mol. Cell. Endocrinol. 307 (1-2), 163-168 (2009)

Background Reference 03

Bellemare, V. J. Steroid Biochem. Mol. Biol. 114 (3-5), 129-134 (2009)

Other Product Names

Estradiol 17-beta-dehydrogenase 12, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, 131-, HSD17B12

Tested Applications

WB, IHC-P, Flow

Protein ID

158931120

Physical Properties

Liquid

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