GALR1 Antibody
Product Specifications
Background
GALR1 elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
NCBI Gene ID
2587
Swiss Prot
P47211
Accession Number
P47211
Host
Rabbit
Reactivity
Human
Immunogen
This GALR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the Central region of human GALR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
GALR1
NCBI Official Name
Galanin receptor type 1
NCBI Organism
Homo sapiens
Background Reference 01
Borroto-Escuela, D.O. Biochem. Biophys. Res. Commun. 393 (4), 767-772 (2010)
Background Reference 02
Gratacos, M. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816
Background Reference 03
Marroni, F. Circ Cardiovasc Genet (4), 322-328 (2009)
Other Product Names
Galanin receptor type 1, GAL1-R, GALR-1, GALR1, GALNR, GALNR1
Tested Applications
WB, Flow
Protein ID
311033447
Physical Properties
Liquid
Frequently Asked Questions
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