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GALR1 Antibody

Product Specifications

Background

GALR1 elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

NCBI Gene ID

2587

Swiss Prot

P47211

Accession Number

P47211

Host

Rabbit

Reactivity

Human

Immunogen

This GALR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the Central region of human GALR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-904

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

GALR1

NCBI Official Name

Galanin receptor type 1

NCBI Organism

Homo sapiens

Background Reference 01

Borroto-Escuela, D.O. Biochem. Biophys. Res. Commun. 393 (4), 767-772 (2010)

Background Reference 02

Gratacos, M. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816

Background Reference 03

Marroni, F. Circ Cardiovasc Genet (4), 322-328 (2009)

Other Product Names

Galanin receptor type 1, GAL1-R, GALR-1, GALR1, GALNR, GALNR1

Tested Applications

WB, Flow

Protein ID

311033447

Physical Properties

Liquid

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