ITPKC Antibody
Product Specifications
Background
ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins (1,4,5) P (3) ] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.
NCBI Gene ID
80271
Swiss Prot
Q96DU7
Accession Number
Q96DU7
Host
Rabbit
Reactivity
Human
Immunogen
This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human ITPKC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-898
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Symbol
ITPKC
NCBI Official Name
Inositol-trisphosphate 3-kinase C
NCBI Organism
Homo sapiens
Background Reference 01
Chi, H. Hum. Mol. Genet. 19 (6), 1147-1151 (2010)
Background Reference 02
Onouchi, Y. Nat. Genet. 40 (1), 35-42 (2008)
Background Reference 03
Nalaskowski, M.M. Biol. Chem. 387 (5), 583-593 (2006)
Other Product Names
Inositol-trisphosphate 3-kinase C, Inositol 1,5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3K C, InsP 3-kinase C, ITPKC, IP3KC
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
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