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ITPKC Antibody

Product Specifications

Background

ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins (1,4,5) P (3) ] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

NCBI Gene ID

80271

Swiss Prot

Q96DU7

Accession Number

Q96DU7

Host

Rabbit

Reactivity

Human

Immunogen

This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human ITPKC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Symbol

ITPKC

NCBI Official Name

Inositol-trisphosphate 3-kinase C

NCBI Organism

Homo sapiens

Background Reference 01

Chi, H. Hum. Mol. Genet. 19 (6), 1147-1151 (2010)

Background Reference 02

Onouchi, Y. Nat. Genet. 40 (1), 35-42 (2008)

Background Reference 03

Nalaskowski, M.M. Biol. Chem. 387 (5), 583-593 (2006)

Other Product Names

Inositol-trisphosphate 3-kinase C, Inositol 1,5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3K C, InsP 3-kinase C, ITPKC, IP3KC

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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