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DDX17 Antibody

Product Specifications

Background

DDX17 box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This protein encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family.

NCBI Gene ID

10521

Swiss Prot

Q92841

Accession Number

Q92841

Host

Rabbit

Reactivity

Human

Immunogen

This DDX17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the N-terminal region of human DDX17.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

DDX17

NCBI Official Name

Probable ATP-dependent RNA helicase DDX17

NCBI Organism

Homo sapiens

Background Reference 01

Wortham, N.C., et.al., Oncogene 28 (46), 4053-4064 (2009)

Background Reference 02

Tonevitsky, E.A., et.al., Bull. Exp. Biol. Med. 147 (6), 733-736 (2009)

Background Reference 03

Wong, H.Y., et.al., Biochim. Biophys. Acta 1794 (2), 193-198 (2009)

Other Product Names

Probable ATP-dependent RNA helicase DDX17, DEAD box protein 17, DEAD box protein p72, RNA-dependent helicase p72, DDX17

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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