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GPX1 Antibody

Product Specifications

Background

GPX1 encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence.

NCBI Gene ID

2876

Swiss Prot

P07203

Accession Number

P07203

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This GPX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human GPX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-890

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

GPX1

NCBI Official Name

Glutathione peroxidase 1

NCBI Organism

Homo sapiens

Background Reference 01

Moyer, A.M., et.al., Cancer Epidemiol. Biomarkers Prev. 19 (3), 811-821 (2010)

Background Reference 02

Akimoto, A.K., et.al., Free Radic. Res. 44 (3), 322-331 (2010)

Background Reference 03

Cao, C., et.al., J. Biol. Chem. 278 (41), 39609-39614 (2003)

Other Product Names

Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase, GPX1

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

311033481

Physical Properties

Liquid

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