VGFR1 Antibody

Product Specifications

Background

VGFR1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes.

NCBI Gene ID

2321

Swiss Prot

P17948

Accession Number

P17948

Host

Rabbit

Reactivity

Human

Immunogen

This VGFR1 antibody is generated from rabbits immunized with human VGFR1 recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

151 kDa

Fragment

Rabbit Ig

Symbol

FLT1

NCBI Official Name

Vascular endothelial growth factor receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Srinivas, S.K., et.al., Am. J. Obstet. Gynecol. 202 (5), 445 (2010)

Background Reference 02

Gomez, L.M., et.al., Am. J. Obstet. Gynecol. 202 (4), 386 (2010)

Background Reference 03

Al-Ani, B., et.al., Hypertension 55 (3), 689-697 (2010)

Background Reference 04

Wong, N.S., et.al., J. Clin. Oncol. 28 (5), 723-730 (2010)

Other Product Names

Vascular endothelial growth factor receptor 1, VEGFR-1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1