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GABRD Antibody

Product Specifications

Background

GABRD is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This protein encodes the delta subunit.

NCBI Gene ID

2563

Swiss Prot

O14764

Accession Number

O14764

Host

Rabbit

Reactivity

Human

Immunogen

This GABRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human GABRD.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

GABRD

NCBI Official Name

Gamma-aminobutyric acid receptor subunit delta

NCBI Organism

Homo sapiens

Background Reference 01

Gratacos, M., et.al., Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009)

Background Reference 02

Maldonado-Aviles, J.G., et.al., AmPsychiatry 166 (4), 450-459 (2009)

Background Reference 03

Tabakoff, B., et.al., BMC Biol. 7, 70 (2009)

Other Product Names

Gamma-aminobutyric acid receptor subunit delta, GABA (A) receptor subunit delta, GABRD

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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