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GABRA2 Antibody

Product Specifications

Background

GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

NCBI Gene ID

2555

Swiss Prot

P47869

Accession Number

P47869

Host

Rabbit

Reactivity

Human

Immunogen

This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-879

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

GABRA2

NCBI Official Name

Gamma-aminobutyric acid receptor subunit alpha-2

NCBI Organism

Homo sapiens

Background Reference 01

Das, S., et.al., Stat Med 29 (11), 1250-1258 (2010)

Background Reference 02

Bierut, L.J., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (11), 5082-5087 (2010)

Background Reference 03

Dixon, C.I., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 2289-2294 (2010)

Other Product Names

Gamma-aminobutyric acid receptor subunit alpha-2, GABA (A) receptor subunit alpha-2, GABRA2

Tested Applications

WB, IHC-P, Flow

Protein ID

126302547

Physical Properties

Liquid

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