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FBXO4 Antibody

Product Specifications

Background

FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.

NCBI Gene ID

26272

Swiss Prot

Q9UKT5

Accession Number

Q9UKT5

Host

Rabbit

Reactivity

Human

Immunogen

This FBXO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-251 amino acids from the Central region of human FBXO4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FBXO4

NCBI Official Name

F-box only protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Zeng, Z., et.al., Dev. Cell 18 (2), 214-225 (2010)

Background Reference 02

Barbash, O., et.al., Cancer Cell 14 (1), 68-78 (2008)

Background Reference 03

Sugiyama, N., et.al., Mol. Cell Proteomics (6), 1103-1109 (2007)

Other Product Names

F-box only protein 4, FBXO4, FBX4

Tested Applications

WB

Protein ID

60416426

Physical Properties

Liquid

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