XDH Antibody
Product Specifications
Background
XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
NCBI Gene ID
7498
Swiss Prot
P47989
Accession Number
P47989
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This XDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the N-terminal region of human XDH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
146 kDa
Fragment
Rabbit Ig
Symbol
XDH
NCBI Official Name
Xanthine dehydrogenase/oxidase
NCBI Organism
Homo sapiens
Background Reference 01
Ross, C.J., et.al., Nat. Genet. 41 (12), 1345-1349 (2009)
Background Reference 02
Taibi, G., et.al., J. Cell. Biochem. 108 (3), 688-692 (2009)
Background Reference 03
Spiekermann, S., et.al., Eur. Respir. J. 34 (1), 276 (2009)
Other Product Names
Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, XD, Xanthine oxidase, XO, Xanthine oxidoreductase, XOR, XDH, XDHA
Tested Applications
WB, IHC-P, Flow
Protein ID
2506326
Physical Properties
Liquid
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