ACCN2 Antibody

Product Specifications

Background

ACCN2 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.

NCBI Gene ID

Swiss Prot

P78348

Accession Number

P78348

Host

Rabbit

Reactivity

Human

Immunogen

This ACCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-526 amino acids from the C-terminal region of human ACCN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Symbol

ASIC1

NCBI Official Name

Acid-sensing ion channel 1

NCBI Organism

Homo sapiens

Background Reference 01

Sherwood, T., et.al., J. Biol. Chem. 284 (41), 27899-27907 (2009)

Background Reference 02

Kapoor, N., et.al., J. Biol. Chem. 284 (36), 24526-24541 (2009)

Background Reference 03

Samways, D.S., et.al., Cell Calcium 45 (4), 319-325 (2009)

Other Product Names

Acid-sensing ion channel 1, ASIC1, Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2, ASIC1, ACCN2, BNAC2

Tested Applications

WB, IHC-P, Flow

Protein ID

296439456

Physical Properties

Liquid

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