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RECK Antibody

Product Specifications

Background

RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.

NCBI Gene ID

8434

Swiss Prot

O95980

Accession Number

O95980

Host

Rabbit

Reactivity

Human

Immunogen

This RECK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-456 amino acids from the Central region of human RECK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-860

Calculated Molecular Weight

106 kDa

Fragment

Rabbit Ig

Symbol

RECK

NCBI Official Name

Reversion-inducing cysteine-rich protein with Kazal motifs

NCBI Organism

Homo sapiens

Background Reference 01

Du, Y.Y., et.al., World J. Gastroenterol. 16 (7), 904-908 (2010)

Background Reference 02

Pesta, M., et.al., Anticancer Res. 29 (11), 4535-4539 (2009)

Background Reference 03

Takahashi, C., et.al., Tanpakushitsu Kakusan Koso 54 (13), 1742-1746 (2009)

Other Product Names

Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK, ST15

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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