RECK Antibody
Product Specifications
Background
RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
NCBI Gene ID
8434
Swiss Prot
O95980
Accession Number
O95980
Host
Rabbit
Reactivity
Human
Immunogen
This RECK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-456 amino acids from the Central region of human RECK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
106 kDa
Fragment
Rabbit Ig
Symbol
RECK
NCBI Official Name
Reversion-inducing cysteine-rich protein with Kazal motifs
NCBI Organism
Homo sapiens
Background Reference 01
Du, Y.Y., et.al., World J. Gastroenterol. 16 (7), 904-908 (2010)
Background Reference 02
Pesta, M., et.al., Anticancer Res. 29 (11), 4535-4539 (2009)
Background Reference 03
Takahashi, C., et.al., Tanpakushitsu Kakusan Koso 54 (13), 1742-1746 (2009)
Other Product Names
Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK, ST15
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Frequently Asked Questions
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