ATXN3 Antibody
Product Specifications
Background
ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG) n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
NCBI Gene ID
4287
Swiss Prot
P54252
Accession Number
P54252
Host
Rabbit
Reactivity
Human
Immunogen
This ATXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the Central region of human ATXN3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-853
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
ATXN3
NCBI Official Name
Ataxin-3
NCBI Organism
Homo sapiens
Background Reference 01
Reina, C.P., et.al, Hum. Mol. Genet. 19 (2), 235-249 (2010)
Background Reference 02
Jung, J., et.al, Hum. Mol. Genet. 18 (24), 4843-4852 (2009)
Other Product Names
Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein, ATXN3, ATX3, MJD, MJD1, SCA3
Tested Applications
WB, IHC-P, Flow
Protein ID
290457685
Physical Properties
Liquid
Curated Selection
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