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ATXN3 Antibody

Product Specifications

Background

ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG) n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.

NCBI Gene ID

4287

Swiss Prot

P54252

Accession Number

P54252

Host

Rabbit

Reactivity

Human

Immunogen

This ATXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the Central region of human ATXN3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

ATXN3

NCBI Official Name

Ataxin-3

NCBI Organism

Homo sapiens

Background Reference 01

Reina, C.P., et.al, Hum. Mol. Genet. 19 (2), 235-249 (2010)

Background Reference 02

Jung, J., et.al, Hum. Mol. Genet. 18 (24), 4843-4852 (2009)

Other Product Names

Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein, ATXN3, ATX3, MJD, MJD1, SCA3

Tested Applications

WB, IHC-P, Flow

Protein ID

290457685

Physical Properties

Liquid

Frequently Asked Questions

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